Subventions et des contributions :

Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019).

The aim of this project is to offer a cost-effective strategy for attaching proteins to glass and plastic substrates (the main substratesx000D
that SQI Diagnostics currently uses) that are stable, functional and properly bond to the substrates. This project will have threex000D
main steps toward reaching this goal: (A) Surface functionalization, (B) Protein immobilization and (C) Bio-functionalityx000D
assessment.x000D
We propose to investigate several functional chemistries on the surfaces for stable and covalent attachment of biomolecules. Wex000D
also propose several methods for the immobilization of biomolecules onto the surfaces such as conventional liquid phase coatingx000D
as well as automated printings for immobilizing SQI's desired biomolecules. As controls, we will also investigate physicalx000D
patterning of the biomolecules on the surface without covalent attachment as well as using the same functional surfaces that thex000D
company is currently using. To demonstrate the bio-functionality, the coatings will be optimized using the currently availablex000D
bioassays at SQI.