Subventions et des contributions :

Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021)

Deformities of the face and skull (craniomaxillofacial, CMF) can result from high impactx000D
trauma, congenital malformations or tumours, which can lead to both functional disabilitiesx000D
and physical disfigurement. Much like a shattered vase, the fractured CMF skeleton requiresx000D
alignment and stabilization of multiple pieces for successful reconstruction. In reconstructivex000D
surgery, generally using plates and screws, complications occur in up to half of all cases. Thex000D
investigators have been working on the development of a composite material (Bone Tape)x000D
for skull surgical reconstruction. The concept is a strong duct tape like device that canx000D
adhere to bone and be used to reattach fractured pieces and hold them stable until they heal.x000D
The properties of the composite offer a unique combination of strength, versatility and ease ofx000D
use, with the flexibility of tape allowing wrapping and bonding to the complex bone contoursx000D
found in the skeleton. The composite is also made of materials that will eventually (andx000D
safely) resorb over time after the fracture has healed, leaving only the mended bones behind.x000D
In developing this concept with industry, the clinicians used some commercial dental bonex000D
cements that are not degradable and may generate residual particulate which the surgeonsx000D
would prefer to be resorbed and eliminated. Hence, there is a need for the conception of ax000D
degradable adhesive polymer with appropriate physical, surface and biocompatibilityx000D
properties that can interphase with composites. This project will ultimately provide thex000D
foundation for such a degradable organic polymer adhesive. Our clinical and scientific team isx000D
committed to translating the novel adhesive along with current composites into practice, inx000D
order to improve treatment and outcomes, with less complications and better lives for thosex000D
recovering from serious CMF injuries and deformities.