Subventions et des contributions :

Titre :
Sperm Olympics: Selecting 1 in 100,000 for Intracytoplasmic Sperm Injection
Numéro de l’entente :
CHRPJ
Valeur d'entente :
272 390,00 $
Date d'entente :
25 avr. 2017 -
Organisation :
Conseil de recherches en sciences naturelles et en génie du Canada
Location :
Ontario, Autre, CA
Numéro de référence :
GC-2017-Q1-00246
Type d'entente :
subvention
Type de rapport :
Subventions et des contributions
Informations supplémentaires :

Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021)

Nom légal du bénéficiaire :
Sinton, David (University of Toronto)
Programme :
Projets de recherche concertée sur la santé
But du programme :

In North America, one in six couples experiences infertility - a 2-fold increase since 1992.x000D
Assisted reproductive technologies (ARTs), such as in vitro fertilization (IVF) andx000D
intracytoplasmic sperm injection (ICSI), require human intervention to manually select spermx000D
in the case of ICSI a single sperm. This manual process is expensive, inefficient, prone tox000D
operator-error and largely random, resulting in sub-optimal pregnancy outcomes andx000D
ultimately the health of offspring. No sperm selection method addresses this growing marketx000D
and medical need. In 2015 we discovered a distinct swimming mode that human sperm use tox000D
navigate confined viscous regions of the female reproductive tract. We have formed a team ofx000D
male fertility, microfluidic engineering, and clinical experts to develop and clinically test ax000D
microfluidic platform that leverages this natural swimming ability to select the highest qualityx000D
sperm cells for direct injection - the Sperm Olympics.