Subventions et des contributions :

Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019).

Near-infrared spectroscopy (NIRS, also known as diffuse optical spectroscopy) is a technique that usesx000D
near-infrared light to measure blood flow and metabolism in body tissues like muscle and brain. NIRS isx000D
non-invasive, invisible to humans, and non-ionizing (that is, it does not cause cancer, unlike ultraviolet light).x000D
An important component of muscle metabolism during exercise is oxygen consumption, which scientists canx000D
measure in order to determine how muscle is responding to exercise and whether a person is benefiting fromx000D
the exercise. One of the standard measurements of muscle oxygen use is the tissue oxygenation index, or TOI.x000D
However, the methods used to determine TOI are not standardized across different NIRS instruments, and thisx000D
limits both its wide applicability and the consistency of the assessments done by various laboratories and sportx000D
scientists. The goal of this research is to establish a new method for calculating TOI using the venousx000D
saturation in presence of cyclic motion. This will allow use of well established and validated techniques inx000D
pulse oximetry to be applied to NIRS. Venous saturation can be measured invasively which allows calibrationx000D
of the method using a gold standard. This will improve the consistency and accuracy of NIRS instruments thatx000D
are used for exercise testing in many settings.