Subventions et des contributions :
Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019).
In spite of considerable advancement in cancer chemotherapy, the survival rate in brain cancer patients isx000D
extremely limited mainly due to the blood-brain barrier (BBB) which prevents the transmission of drug fromx000D
blood circulation into the brain parenchyma. The present research proposal is based on the conjugation ofx000D
TRIOZANTM, as a nanomedicine delivery platform under proprietary of Ovensa Inc., with B1R agonist ligand.x000D
The permeability of B1R-functionalized TRIOZANTM will be evaluated via the measurement of its bindingx000D
affinity to the endothelial cell receptors. Developed technology will be transferred to Ovensa Inc. as a key stepx000D
in developing of blood-brain-transient drug delivery platform.