Subventions et des contributions :

Titre :
Scalable Acoustic Microscopy for Pharmaceutical Applications
Numéro de l’entente :
EGP
Valeur d'entente :
25 000,00 $
Date d'entente :
22 mars 2018 -
Organisation :
Conseil de recherches en sciences naturelles et en génie du Canada
Location :
Québec, Autre, CA
Numéro de référence :
GC-2017-Q4-01729
Type d'entente :
subvention
Type de rapport :
Subventions et des contributions
Informations supplémentaires :

Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019).

Nom légal du bénéficiaire :
Sylvestre, Julien (Université de Sherbrooke)
Programme :
Subventions d'engagement partenarial pour les universités
But du programme :

Various containers, such as glass vials and plastic bags, are used in large quantities by the pharmaceuticalx000D
industry to manufacture and distribute sterile products. Structural weaknesses or defects in these containers canx000D
compromise the integrity of the pharmaceutical products. When detected during the manufacturing phase,x000D
compromised products have to be discarded and result in significant monetary losses. When they gox000D
undetected, compromised products jeopardize patient safety. As a result, manufacturers of pharmaceuticalx000D
products and suppliers of glass or plastic containers invest significant efforts to control the quality of containersx000D
and packaged products, before, during and after the manufacturing process. Many of the most important classesx000D
of defects are difficult to detect with conventional methods, such as optical inspection. Examples includex000D
hairline cracks or voids in the walls of glass vials, voids in plastic bag seals, glass vial walls or plastic bags thatx000D
are too thin, and small glass particles mixed with the pharmaceutical product inside glass vials. The industry isx000D
therefore looking for other inspection technologies that could provide quality information which is orthogonalx000D
to what is provided by optical methods, to better detect hard-to-find defects. The main research challenges to bex000D
addressed through the project therefore include the use of quality control technologies for pharmaceuticalx000D
containers based on acoustic microscopy, which have high sensitivity to defects, low false positive rates, andx000D
which are fast enough for high-volume manufacturing.